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Publications
A viral assembly inhibitor blocks SARS-CoV-2 replication in airway epithelial cells
https://nature.com/articles/s42003-024-06130-8 The ongoing evolution of SARS-CoV-2 to evade vaccines and therapeutics underlines the need...
Inhibition of mRNA nuclear export promotes SARS-CoV-2 pathogenesis
https://www.pnas.org/doi/10.1073/pnas.2314166121 The nonstructural protein 1 (Nsp1) of SARS-CoV-2 (Severe Acute Respiratory Syndrome...
SARS-CoV-2 Inhibitors Identified by Phenotypic Analysis of a Collection of Viral RNA-Binding Molecules
https://pubmed.ncbi.nlm.nih.gov/36558898/ Antiviral agents are needed for the treatment of SARS-CoV-2 infections and to control other...
Protocol for production and purification of SARS-CoV-2 3CLpro
https://pubmed.ncbi.nlm.nih.gov/37235475/ 3CLpro protease from SARS-CoV-2 is a primary target for COVID-19 antiviral drug development....
Structural similarities between SARS-CoV2 3CLpro and other viral proteases suggest potential lead molecules for developing broad spectrum antivirals
https://pubmed.ncbi.nlm.nih.gov/36353143/ Considering the significant impact of the recent COVID-19 outbreak, development of...
Ancestral, Delta, and Omicron (BA.1) SARS-CoV-2 strains are dependent on serine proteases for entry throughout the human respiratory tract
https://pubmed.ncbi.nlm.nih.gov/37769654/ The SARS-CoV-2 Omicron BA.1 variant emerged in late 2021 and became the globally dominant...
Parallel use of human stem cell lung and heart models provide insights for SARS-CoV-2 treatment
https://pubmed.ncbi.nlm.nih.gov/37315523/ Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily infects the respiratory...
Identification of In Vitro Inhibitors of Monkeypox Replication
Identification of In Vitro Inhibitors of Monkeypox Replication - PubMed ( nih.gov ) Monkeypox virus (MPXV) infections in humans have...
Inhibition of SARS-CoV-2 growth in the lungs of mice by a peptide-conjugated morpholino oligomer targeting viral RNA
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(24)00218-X Further development of direct-acting antiviral...
Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection
https://pubmed.ncbi.nlm.nih.gov/36175661/
SARS-CoV-2 Inhibitors Identified by Phenotypic Analysis Collection of Viral RNA-Binding Molecules
https://www.mdpi.com/1424-8247/15/12/1448
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